时间：2021年7月10日下午13:30
讲座地点：生科大楼317会议室
题目：人类糖组的酶法模块化组装
报告人：曹鸿志 中国海洋大学医药学院教授，国际糖科学专业杂志Carbohydrate Research和Journal of Carbohydrate Chemistry编委，中国化学会糖化学专业委员会秘书长，曾获日本Mizutani基金会Research Grant Award，中国化学会—巴斯夫公司青年知识创新奖，“张树政糖科学奖”优秀青年奖等奖项，在Nat. Catal.，JACS等国际知名期刊发表60余篇SCI论文。曹鸿志课题组主要从事具有重要生物学功能糖链的无细胞生物合成和糖化学生物学相关领域的研究。
近期代表性论文：
1.Jinfeng Ye, Hui Xia, Na Sun, Chang-Cheng Liu, Anran Sheng, Lianli Chi, Guofeng Gu, Shuqi Wang, Xian-Wei Liu, Jie Zhao, Ping Wang, Min Xiao, Fengshan Wang,Hongzhi Cao*. Reprogrammingtheenzymatic assembly line for site specific fucosylation.Nature Catal.2019,2, 514-522.
2.Na Lu, Jinfeng Ye, Jiansong Cheng, Aniruddha Sasmal, Chang-Cheng Liu, Wenlong Yao, Jun Yan, Naazneen Khan, Wen Yi, Ajit Varki,Hongzhi Cao*. Redox-controlled site-specific α2,6-sialylation.J. Am. Chem. Soc.2019, 141, 4547−4552.
3.Tian Gao, Jingyu Yan, Chang-Cheng Liu, Angelina S. Palma, Zhimou Guo, Min Xiao, Xi Chen, Xinmiao Liang, Wengang Chai, Hongzhi Cao*. Chemoenzymatic synthesis of O-mannose glycans containing sulfated or nonsulfated HNK-1 epitope.J. Am. Chem. Soc.2019, 141, DOI: 10.1021/jacs.9b08964.
Caicai Meng, Aniruddha Sasmal, Yan Zhang, Tian Gao, Chang-Cheng Liu, Naazneen Khan,Ajit Varki, Fengshan Wang,*Hongzhi Cao*. Chemoenzymatic assembly of mammalian O-mannose glycans.Angew. Chem. Int. Ed.2018, 57, 9003-9007
